剌婷

临床职称: 副研究员 

科室:生物诊疗中心  

专业特长: 细胞休眠代谢、结肠癌、等肿瘤相关疾病

    剌婷，女，医学生物化学博士，毕业于澳大利亚纽卡斯尔大学。澳大利亚纽卡斯尔大学博士后。硕士毕业于上海交通大学医学院。现任西安交通大学第二附属医院副研究员。主持中国国家自然科学基金面上项目和青年项目各1项；澳大利亚HMRI Researcher Bridging Funds；BIOMARKERS AND TARGETED THERAPIES FLAGSHIP 2019 Project Funding Round等。

发表论文21篇，累计影响因子653；Hindex:12

电子邮箱:ting.la@uon.edu.au; lating2011@hotmail.com

1.La T#,Chen S#, Zhao XH, Zhou S, Xu R, Teng L, Zhang YY, Ye K, Xu L, Guo T, Jamaluddin MF, Feng YC, Tang HJ, Wang Y, Xu Q, Gu Y, Cao H, Liu T, Thorne RF, Shao FM, Zhang XD, Jin L, LncRNA LIMp27 Regulates the DNA Damage Response through p27 in p53-Defective Cancer Cells. Adv. Sci. 2023, Mar;10(7):e2204599. (IF=17.521, #共同第一作者)

2. Wang PL, Teng L, Feng YC, Yue YM, Han MM, Yan Q, Ye K, Tang CX, Zhang SN, Fei Qi T, Zhao XH,La T,Zhang YY, Li JM, Hu B, Xu D, Cang S, Wang L, Jin L, Thorne RF, Zhang Y, Liu T, Zhang XD. The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining. Proc Natl Acad Sci U S A.2022 Dec 6;119(49):e2208904119. (IF=12.779)

3.La T#,Chen S#, Guo T, Zhao XH, Teng L, Li D, Carnell M, Zhang YY, Feng YC, Cole N, Brown AC, Zhang D, Dong Q, Wang JY, Cao H, Liu T, Thorne RF, Shao FM, Zhang XD, Jin L. Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells.Theranostics.2021 Sep 21;11(19):9605-9622. (IF=11.6, #共同第一作者)

4.La T,Liu GZ, Farrelly M, Cole N, Feng YC, Zhang YY, Sherwin SK, Yari H, Tabatabaee H, Yan XG, Guo ST, Liu T, Thorne RF, Jin L, Zhang XD. A p53-Responsive miRNA Network Promotes Cancer Cell Quiescence.Cancer Res.2018 Dec 1;78(23):6666-6679. (IF=13.312)

5.La T,* Jin L, Liu XY, Song ZH, Farrelly M, Feng YC, Yan XG, Zhang YY, Thorne RF, Zhang XD, Teng L*. Cylindromatosis Is Required for Survival of a Subset of Melanoma Cells.Oncol Res.2020 Sep 1;28(4):385-398. (IF=4.938, *通讯作者)

6.Cao B, Bai C, Wu K, La T, Su Y, Che L, Zhang M, Lu Y, Gao P, Yang J, Xue Y, Li G. Tracing the future of epidemics: Coincident niche distribution of host animals and disease incidence revealed climate-correlated risk shifts of main zoonotic diseases in China. Glob Chang Biol. 2023 Apr 7. doi: 10.1111/gcb.16708. Epub ahead of print. PMID: 37026556. (IF=13.211)

7. Teng L, Feng YC, Guo ST, Wang PL, Qi TF, Yue YM, Wang SX, Zhang SN, Tang CX,La T,Zhang YY, Zhao XH, Gao JN, Wei LY, Zhang D, Wang JY, Shi Y, Liu XY, Li JM, Cao H, Liu T, Thorne RF, Jin L, Shao FM, Zhang XD. The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis.Nat Commun.2021 Jun 18;12(1):3734. (IF=17.694)

8. Chen J, Nelson C, Wong M, Tee AE, Liu PY,La T,Fletcher JI, Kamili A, Mayoh C, Bartenhagen C, Trahair TN, Xu N, Jayatilleke N, Wong M, Peng H, Atmadibrata B, Cheung BB, Lan Q, Bryan TM, Mestdagh P, Vandesompele J, Combaret V, Boeva V, Wang JY, Janoueix-Lerosey I, Cowley MJ, MacKenzie KL, Dolnikov A, Li J, Polly P, Marshall GM, Reddel RR, Norris MD, Haber M, Fischer M, Zhang XD, Pickett HA, Liu T. Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.Clin Cancer Res.2021 Mar 1;27(5):1438-1451. (IF=13.801)

9. Feng YC, Liu XY, Teng L, Ji Q, Wu Y, Li JM, Gao W, Zhang YY,La T,Tabatabaee H, Yan XG, Jamaluddin MFB, Zhang D, Guo ST, Scott RJ, Liu T, Thorne RF, Zhang XD, Jin L. c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis.Nat Commun.2020 Oct 5;11(1):4980. (IF=17.694)

10. Yari H, Jin L, Teng L, Wang Y, Wu Y, Liu GZ, Gao W, Liang J, Xi Y, Feng YC, Zhang C, Zhang YY, Tabatabaee H,La T,Yang RH, Wang FH, Yan XG, Farrelly M, Scott R, Liu T, Thorne RF, Guo ST, Zhang XD. LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription.Nat Commun.2019 Nov 25;10(1):5334. (IF=17.694)

11. Wang JY, Liu GZ, Wilmott JS,La T,Feng YC, Yari H, Yan XG, Thorne RF, Scolyer RA, Zhang XD, Jin L. Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.Cancer Res.2017 Nov 15;77(22):6226-6239. (IF=13.312)

12. Wang Y, Feng YC, Gan Y, Teng L, Wang L,La T,Wang P, Gu Y, Yan L, Li N, Zhang L, Wang L, Thorne RF, Zhang XD, Cao H, Shao FM. LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma.J Exp Clin Cancer Res.2022 Aug 26;41(1):260. (IF=12.658)

13. Chen K, Zhang W,La T,Bastians PA, Guo T, Cao C. Microstructure investigation of plant architecture with X-ray microscopy.Plant Sci.2021 Oct;311:110986. (IF=5.363)

14. Li D, Hu LN, Zheng SM,La T,Wei LY, Zhang XJ, Zhang ZH, Xing J, Wang L, Li RQ, Zhu Q, Thorne RF, Feng YC, Hondermarck H, Zhang XD, Li L, Gao JN. High nerve density in breast cancer is associated with poor patient outcome.FASEB Bioadv.2022 Mar 3;4(6):391-401.

15. Wang JY, Jin L, Yan XG, Sherwin S, Farrelly M, Zhang YY, Liu F, Wang CY, Guo ST, Yari H,La T,McFarlane J, Lei FX, Tabatabaee H, Chen JZ, Croft A, Jiang CC, Zhang XD. Reactive Oxygen Species Dictate the Apoptotic Response of Melanoma Cells to TH588.J Invest Dermatol.2016 Nov;136(11):2277-2286. (IF=7.59)

16. Liu F, Jiang CC, Yan XG, Tseng HY, Wang CY, Zhang YY, Yari H,La T,Farrelly M, Guo ST, Thorne RF, Jin L, Wang Q, Zhang XD. BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma.Oncotarget.2017 May 9;8(41):69477-69492. (IF=3.331)

17. Sun ZC, Ge JL, Guo B, Guo J, Hao M, Wu YC, Lin YA,La T,Yao PT, Mei YA, Feng Y, Xue L. Extremely Low Frequency Electromagnetic Fields Facilitate Vesicle Endocytosis by Increasing Presynaptic Calcium Channel Expression at a Central Synapse.Sci Rep.2016 Feb 18;6:21774. (IF=4.996)

18. Zhang F, Wu L, Qian J, Qu B, Xia S,La T,Wu Y, Ma J, Zeng J, Guo Q, Cui Y, Yang W, Huang J, Zhu W, Yao Y, Shen N, Tang Y. Identification of the long noncoding RNA NEAT1 as a novel inflammatory regulator acting through MAPK pathway in human lupus.J Autoimmun.2016 Dec;75:96-104. (IF=14.511)

19. Wang CY, Guo ST, Wang JY, Yan XG, Farrelly M, Zhang YY, Liu F, Yari H,La T,Lei FX, Jin L, Zhang XD, Jiang CC. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.Oncotarget.2016 Aug 2;7(31):49597-49610. (IF=3.331)

20.剌婷,马健阳,沈南,唐元家.利用CRISPR/Cas9系统和TALEN技术干预XIST基因的表达。中国细胞生物学学报.2014, 36 (12): 1652-1660.

21. 左炽健,剌婷,张宁,戴尅戎,张晓玲.MSCs成骨分化中BMP2对成骨转录因子SATB2表达的调控作用.上海交通大学学报（医学版）. 2011, 31 (12): 1661-1666.